TAMs produce growth and survival factors for tumor cells (epidermal growth factor (EGF), fibroblast growth factor (FGF), interleukin (IL)-6, and IL-8) and angiogenic factors (EGF, FGF, vascular endothelial growth factor (VEGF), and platelet-derived growth factor (PDGF)) and suppress the T-cell-dependent antitumor immunity [76]. Here, EGF is linked to neoplasm.