On the other hand, TGFβ can enhance the malignant growth of some established epithelial tumors, promoting tumor cell proliferation, migration, and the epithelial-to-mesenchymal transition (EMT)—a process by which advanced carcinomas acquire a highly invasive and undifferentiated phenotype and become metastatic [80,81]. The gene discussed is TGFB1; the disease is carcinoma.