The shorter period of white blood cell doubling in peripheral blood (10.7 vs. 18.0; p < 0.001), frequent infectious episodes, lymphadenopathy and hepatosplenomegaly (37 vs. 16), higher expression for CD38, and lower for ZAP-70 antigens were among the peculiarities, although not statistically significant. The gene discussed is ZAP70; the disease is Lymphadenopathy.