NTRK1 and neoplasm: Recently, Russo et al. reported that the profile of the LMNA-NTRK1 rearrangement in ctDNAs paralleled tumor response and resistance to entrectinib (RXDX-101, previously known as NMS-E628), a potent pan tropomyosin-related kinase (TRK), ALK, and ROS1 inhibitor [124].