In males, the univariate analysis observed ten factors to be significantly associated with low GS (<26 kg): Age (P < 0.0001), BMI (P = 0.0357), presence of LC (P < 0.0001), serum albumin level (P < 0.0001), prothrombin time (PT, P = 0.0013), platelet count (P = 0.0025), M2BPGi (P < 0.0001), FIB-4 index (P < 0.0001), estimated glomerular filtration rate (P = 0.0249) and SMI (P = 0.0028). The gene discussed is F2; the disease is laryngotracheoesophageal cleft.