PDCD1 and non-small cell lung carcinoma: In NSCLC, the expression of T-cell effector molecules, including PD-1 (PDCD1), granzyme A (GZMA), granzyme B (GZMB), perforin (PRF1), IFNγ (IFNG), CXCL9, and CXCL10, correlated inversely with MET expression, especially in the PD-L1high vs. PD-L1low group (Figure 6A).