CEACAM5 and medullary thyroid gland carcinoma: The first study was performed by Kraeber-Bodéré et al. who confirmed that repeated treatments of PRIT based on the AES with murine anti-CEA × anti-DTPA-In bsAbs and iodine-131-labeled haptens in mice xenografted with human MTC led to high antitumor efficiency without a significant increase in toxicity [54].