Of note, OC inhibits cell growth more effectively than classic pharmaceutical COX inhibitors; in addition, OC inhibits colony formation and induces apoptosis-by PARP cleavage, activation of caspases 3/7, and chromatin condensation—in hepatocellular carcinoma (HCC) and colorectal cancer (CRC) cells. The gene discussed is CASP3; the disease is hepatocellular carcinoma.