Evaluation of the CYP4 expression profile in hepatocellular carcinoma (HCC) showed that CYP4F2, CYP4F12, and CYP4V2 mRNA levels were negatively correlated with cell-cycle-associated genes, suggesting that these CYP4 genes are favorable prognostic factors in HCC [76]. This evidence concerns the gene CYP4F12 and hepatocellular carcinoma.