PTX3 and breast cancer: Based on these observations, a cohort of 62 human BC samples, including five low-grade papillary NMIBCs, 17 high-grade NMIBCs, and 40 MIBCs, were examined for the presence of PTX3 by immunohistochemistry and scored for PTX3 positivity (i.e., no presence, mild positivity, or high positivity; see Table S2).