BARD1 and cutaneous mastocytosis: We found that the known NB susceptibility gene BARD1 (2q35) [4,56] lies in close proximity to a candidate susceptibility locus for CM; copy number alterations at the BARD1 locus have been previously associated to developmental delay, coarctation of aorta and ToF [57], suggesting a role of BARD1 in early organogenesis and heart formation.