CLDN3 and neoplasm: In a previous work, we showed that a recombinant produced C-terminus (D194-F319) of the Clostridium perfringens enterotoxin (C-CPE) could be used to functionalize gold nanoparticles (AuNPs) for a subsequently optoperforation-induced killing of tumor cells expressing the CPE receptors, claudin-3, -4, and -7 using GNOME-LP [4].