Among them, we were interested in lncRNA TCONS_ 00010987, because the cis mechanism prediction indicated that its potential target gene was LEPR. Considering the physiological and clinical importance of this gene in regulating obesity and the fact that porcine LEPR expression has not been previously shown to be under lncRNA control, we conducted a bioinformatic analysis to predict miRNAs that could bind SSC-TCONS_00010987-target sequence fragments and the SSC-LEPR-3′-UTR. This evidence concerns the gene LEPR and obesity due to melanocortin 4 receptor deficiency.