TLR3 and viral infectious disease: Also, the up-regulation of chLECT2 expression after the stimulation of poly (I:C) suggests that this gene might be related to viral infection in chickens, and the significantly lower expressional level of chLECT2 under the presence of transcriptional inhibitors, Bay and Tan-II verifies that the expression of this gene is involved in TLR3 signal pathway.