The multivariate cox regression model that included age, tumor localization, IDH1/2 mutation status, and MALAT1 expression status showed that high MALAT1 expression was a significant predictor of poor prognosis in patients with primary GB, with the median follow-up period of 60 months (N = 75; p = 0.034; Table 4). This evidence concerns the gene MALAT1 and neoplasm.