Mutations in KCNJ10, which codes for the glial‐specific Kir4.1 channel, underlie SeSAME/EAST syndrome (seizures, sensorineural deafness, ataxia, intellectual disability and electrolyte imbalance/epilepsy, ataxia, sensorineural deafness, and tubulopathy) (Bockenhauer et al., 2009; Scholl et al., 2009) and have been detected in patients diagnosed with autism spectrum disorder and epilepsy (Sicca et al., 2011, 2016). This evidence concerns the gene KCNJ10 and Abnormality of metabolism/homeostasis.