In line with human HCC patient expression data (Figure 1C and Figure 1—figure supplement 4A), we found that in established liver tumors derived from Alb-cre;KrasG12D mice, Snora24 was significantly decreased in tumor tissue compared to liver tissue from wild-type mice (Figure 2D, n = 3 mice per condition). This evidence concerns the gene ALB and hepatocellular carcinoma.