In contrast to LNA-ctrl treated SB(+)NRASG12V mice, which have normal livers and do not show any signs of HCC (Figure 2A, bottom left panel, representative image from n = 8 mice), we found that a reduction in Snora24 cooperates with RASG12V to promote the development of liver cancer in all LNA-24 treated SB(+)NRASG12V mice examined (Figure 2A, bottom right panel, representative image from n = 8 mice). The gene discussed is SNORA24; the disease is liver cancer.