Real-time PCR showed significant up-regulation of both ESRP1 and ESRP2 mRNA in (1) prostate carcinoma relative to benign prostate hyperplasia (BPH) (Figure 2A); and (2) in nine prostate tumour samples relative to matched normal tissue from the same patient (Figure 2B). This evidence concerns the gene ESRP1 and prostate neoplasm.