In this hospital‐based case–control study, we investigated the association of four important polymorphisms (rs10006115, rs4604006, rs12646659, and rs11955717) with the risk of cervical cancer in Chinese Uygur population, and we observed a significant association between the VEGF‐C rs12646659 polymorphism and the risk of cervical cancer. The gene discussed is VEGFC; the disease is cervical cancer.