The comparison of allele distributions between the cervical cancer patients and the control subjects with the χ2‐test revealed that there was a statistical correlation between the rs12646659 polymorphism of VEGF‐C and the risk reduction of cervical cancer (OR = 0.41, 95% CI = 0.20–0.87; p = .017). The gene discussed is VEGFC; the disease is cervical carcinoma.