LCT and type 2 diabetes mellitus: The association of dairy products with T2D incidence may be modified by the genetic variant rs4988235 near the lactase persistence LCT gene.31 In a large Danish study, carriers with the lactase persistence LCT rs4988235 T‐allele had higher T2D risk compared with persons with the lactose nonpersistence CC‐genotype when they did not consume milk.31 A contrasting reduced risk was observed among milk consumers.31 Coffee intake is hypothesized to reduce T2D risk, and findings from EPIC‐InterAct24 and KARE32 indicate that there exist interactions of coffee with some genetic variants.