In both studies, participants with the TCF7L2 rs12255372 risk TT‐genotype showed lower T2D incidence in the intervention group than in the control group.59, 60 Similar findings were reported for persons with the rs7903146 risk T‐allele by DPP and the Asti study.58, 59 However, the corresponding interaction tests were not significant.58, 59, 60. Here, TCF7L2 is linked to type 2 diabetes mellitus.