Four proteins were selected based on literature data, where studies of MDS serum21 and proteomic studies of MDS plasma22 have revealed intracellular adhesion molecule 1 (ICAM), vascular cell adhesion protein 1 (VCAM), alpha-2-HS-glycoprotein (fetuin), and leucine-rich alpha-2-glycoprotein (LRG) as promising candidates. Here, LRG1 is linked to myelodysplastic syndrome.