In contrast to healthy donor plasma, we identified the following proteins in MDS plasma: clusterin, protein S100A8, hornerin, serum amyloid A-1 protein, annexin A2, zinc-alpha-2-glycoprotein, gamma-glutamylcyclotransferase, ubiquitin-40S ribosomal protein S27a, etc. (Tables 2 and 3). Here, HRNR is linked to myelodysplastic syndrome.