Despite findings that overexpression of clusterin is attributed to tumor formation, development, and metastasis35, and that silencing of clusterin can effectively induce apoptosis and inhibit the proliferation and invasion of HL-60 acute myeloid leukemia cells24, we did not find any significant differences of SPR sensor responses among the MDS subgroups for immobilized clusterin. Here, CLU is linked to acute myeloid leukemia.