EI-78 - Compared to untreated AMD cybrids, significant IL-18 downregulation was observed in PU-91-treated, P+EI-78 2.5 μM (34.6%), P+EI-78 5 μM (45%), and P+EI-78 10 μM (61%) groups (Figure 9C, Supplementary Table 5). This evidence concerns the gene IL18 and age-related macular degeneration.