CASP3 and age-related macular degeneration: EI-78 - Compared to untreated AMD cybrids, significant Caspase-3 downregulation was observed in PU-91-treated, P+EI-78 2.5 μM (26%), P+EI-78 10 μM (34%), and only EI-78 10 μM (13.8%) groups (Figure 9B, Supplementary Table 5).