CACNA1A and nervous system disorder: Considering the interaction between Cav2.1 and AnkB and the overlap in neurological disorders caused by variants in their respective genes, we explored the relationship between Cav2.1 and AnkB at the subcellular level using transient expression in HEK293T cells and AnkB cortex-specific (Emx1-Cre) heterozygous knockout mice.