In addition, the lateral flow urine lipoarabinomannan assay (LF-LAM) may be used to assist in the diagnosis of TB in HIV positive adult in-patients with signs and symptoms of TB who have a CD4 count ≤100 cells/μL, or HIV positive patients who are seriously ill regardless of CD4 count or with unknown CD4 count [26]. The gene discussed is CD4; the disease is tuberculosis.