The primary aim of the present study was to determine whether any association existed between certain single nucleotide polymorphisms (SNPs) of the CYP19A1, CYP2C19, CYP2C9, CYP1B1, CYP3A4, and CYP1A2 genes and BC in the Jordanian population. The gene discussed is CYP1A2; the disease is breast cancer.