FBN1 and Marfan syndrome: The classical example of syndromic TAAD with a single gene mutation is Marfan syndrome (MFS), caused by mutations in FBN1, the gene encoding for fibrillin‐1, an extracellular matrix protein (Cook, Carta, Galatioto, & Ramirez, 2015; De Paepe, Devereux, Dietz, Hennekam, & Pyeritz, 1996; Erbel et al., 2014; Loeys et al., 2010).