Recent publications further report developmental delay, pain insensitivity, and mitochondrial respiratory chain complex IV deficiency phenotypes (Sheffer et al., 2016); refractory epilepsy (Vanstone et al., 2016); slowly progressive mild neurological impairment (Nasca et al., 2016), and childhood onset epileptic encephalopathy (Fahrner, Liu, Perry, Klein, & Chan, 2016) in patients with DNM1L variants. Here, DNM1L is linked to hyperinsulinemic hypoglycemia, familial, 4.