ABCG2 and pancreatic neoplasm: Meanwhile, high expression of several important multidrug resistance transporter efflux chemotherapy drugs, such as ABCG2, has been reported on the surface of CSCs.68 A novel ABCG2 nonsubstrate antitumor molecule (FL118) reverses resistance to GEM in pancreatic cancer via complex mechanisms, one of which is reducing stem‐like pancreatic cancer cell populations.69