DYSF and autosomal recessive limb-girdle muscular dystrophy type 2B: It was initially found to have a high degree of homology to dysferlin, and the percentage of similarity between myoferlin and dysferlin sequences is 69%.1 Dysferlin gene mutations cause Miyoshi myopathy and limb girdle muscular dystrophy type 2B,2 while mutations in myoferlin are not correlated with human disease in previous studies.