Elimination of myoferlin in mice results in smaller myofibres and a dystrophic phenotype that has a decreased capacity to regenerate after injury.3 In the hindlimb muscles of resistance exercise‐trained rats, myoferlin mRNA was highly up‐regulated.4 In quadriceps biopsies from Duchenne muscular dystrophy patients, myoferlin mRNA was also up‐regulated 7.3‐fold.5 Of note, recent studies suggest that myoferlin participates in the proliferation, invasion and metastasis of multiple cancers. This evidence concerns the gene MYOF and Duchenne muscular dystrophy.