It was initially found to have a high degree of homology to dysferlin, and the percentage of similarity between myoferlin and dysferlin sequences is 69%.1 Dysferlin gene mutations cause Miyoshi myopathy and limb girdle muscular dystrophy type 2B,2 while mutations in myoferlin are not correlated with human disease in previous studies. This evidence concerns the gene MYOF and autosomal recessive limb-girdle muscular dystrophy type 2B.