SLC27A3 and central nervous system cancer: Glioma cells treated with CPT1 inhibitor etomoxir exhibited inhibited growth.22, 23 Acyl‐CoA synthetase homolog 3 (ACSVL3), which adds coenzyme A to fatty acids, was also over‐expressed and involved in regulation of self‐renewal maintenance in glioma.24, 25 Expression of fatty acid synthase (FASN) increased with tumour grade, and pharmacological inhibition of FASN significantly decreased the proliferation and migration of glioma stem cells.26, 27 In this study, we profiled the lipid metabolism phenotype between low‐grade glioma and GBM with gene expression data.