CD1A and central nervous system cancer: It should be noted that the CD1A isoforms, CD1A6 and CD1A8, were reported individually in canine ODG, however, human data was only available for CD1A. CD93 demonstrated significant upregulation in all human glioma subtypes: GBM (p-value 0.0001), ODG (p-value 0.03), OA (p-value 0.02), and AA (p-value 0.01).