CXCR4 and neoplasm: Figure 2 shows concordant cases of immunohistochemistry and non-invasive imaging in patients suffering from CCC (patient #7) and HCC (patient #17), respectively. Figure 3 demonstrates CXCR4-directed imaging in further selected tumor entities which (with the exception of patient #9 suffering from low-grade ovarian carcinoma) primarily demonstrated moderate to no uptake on CXCR4-directed imaging.