It has been shown that the ratio of SP-A1 to SP-A differs in lung diseases (23, 24), and this may have functional consequences given the varying activities of SP-A1 and SP-A2, (e) we did not study the impact of gonadectomy on the expression of AM miRNAs from co-ex and KO males and females. The gene discussed is SFTPA1; the disease is lung disorder.