FCGR2A and systemic lupus erythematosus: The data showed that systemic lupus erythematosus pathway was significantly down-regulated and suggest the several signaling pathways associated with NLRP3 inflammasome activation on MAPK, ECM-receptor interaction, cell adhesion molecules, Toll-like receptor, FcγR-mediated phagocytosis and leukocyte transendothelial migration may all contribute to the mechanism of action of the potential renoprotective effects of M1 in the treated ASLN mice (Supplementary Table S1).