In untreated conditions, granulomas were composed of 14.19 ± 2.43% of CD4+ T cells, 12.51 ± 2% of CD8+ T cells, 2.84 ± 0.57% of B cells, and 11.18 ± 1.81% of CD68+ macrophages (Figure 2A). This evidence concerns the gene CD4 and Granuloma.