PLA2R1 and idiopathic membranous glomerulonephritis: In another small study of 24 patients with recurrent (n = 12) or de novo membranous GN (n = 12), glomerular staining for PLA2R was more common in those with recurrent disease (83% cases, sensitivity and specificity of 83% [95%CI 51–97%] and 92% [95%CI 60–100%], respectively) compared to de novo disease (17%), and suggest that injury to the podocytes occurring post-transplantation triggering the release of podocyte antigens may induce the formation of auto-antibodies and deposition of subepithelial immune complexes (193, 196).