Other transcripts were also detected at increased levels, including chemokine transcripts CXCL9, CXCL10 (among the top-ranked expressed genes), CXCL1, and CCL5. The network of highly modulated genes was further analyzed with the ViaComplex software, which compared the transcriptional profile of infected vs. uninfected cells plotting the mean expression values (Z-axis) as a 3D landscape topographical view, this analysis showed the cluster of type-I IFN response as the highest level of expression induced by infection (Figures 2B,C). Here, CXCL1 is linked to infection.