TBX21 and myeloid sarcoma: While the probe for Tbet/TBX21 [implied in Th1 differentiation and CD8 T cell effector function (12)] did not display detectable signals to be analyzed, those for GATA-3 [implied in Th2 differentiation and CD8 T cell survival, (12, 13)], Foxp3 [expressed by CD4 and CD8 regulatory T cells (14, 15) and RORA [a master gene for IL17 production (16, 17)], displayed equal expression in PBMC of healthy and PP-MS subjects (Figures 2A–C).