ITGB3 and psoriasis: Indeed, compared to whole blood staining, where psoriasis patient samples showed higher CD41 and CD61 expression than healthy donors (Figure 2A), Ficoll purification reduced these differences in CD41 and CD61 staining between psoriasis patients and healthy donors: Ficoll-purified PMNs showed more similar levels of CD41 and CD61 positivity between the two groups (Figure 2B).