Albeit in a different disease setting, it has been also reported that monocytes recruit neutrophils in a TLR7-dependent manner through CXCL1 (60), different from the case of cancer context where non-classical monocytes-derived CXCL5 was newly discovered as the key chemokine attracting neutrophils (7, 8). The gene discussed is CXCL5; the disease is cancer.