STK11 and lung carcinoma: In STK11/LKB1-deficient KP lung carcinoma, recruited neutrophils produce suppressive factors such as IL-10, LGALS9, Arginase1 (ARG1), and Milk fat globulin EGF factor (MFGE8) which are also involved in cytotoxic T cell suppression as well as the tumor-promoting cytokine IL-6 (92).