Our study failed to demonstrate any alteration in adiponectin concentration and additional studies are necessary once the controversial results remain in literature and have difficulties in associating circulatory adiponectin levels as a biomarker of cardiovascular disease and vascular dysfunction (Sattar et al., 2006; Sook Lee et al., 2013; Woodward et al., 2016). The gene discussed is ADIPOQ; the disease is cardiovascular disorder.