AcSDKP inhibits EndMT-driven renal fibrosis by ameliorating the miR-let-7 family clusters (Nagai et al., 2014; Nitta et al., 2016; Li et al., 2017) and the miR-let-7s-FGFR1 axis inhibits TGFβ signaling in fibrotic kidneys (Nagai et al., 2014). Here, TGFB1 is linked to renal fibrosis.