HELB and Anxiety: We recently demonstrated that SPX1 neurons are located in the specific nuclei of dHb, which regulates fear and anxiety, and dHb SPX1 neurons project their axons to the galanin receptor 2a/2b (GALR2a/2b) neurons in the IPN of the zebrafish brain (Pandey et al., 2018; Kim et al., 2019).