Data showed that PA did not significantly increase the proliferation of the PCa cells that were overexpressed with STAT3-Y705F (Fig. 5e, f) or those overexpressed with STAT3-R593A (Fig. 5g, h) or STAT3-N538A (Fig. 5i, j) or double mutations R593A + N538A (Fig. 5k, n). This evidence concerns the gene STAT3 and posterior cortical atrophy.