DDIT3 and anaplastic large cell lymphoma: We first assessed the sensitivity of a panel of malignant T-cell lines (HH, cutaneous TCL; SUP-T1, lymphoblastic TCL; KARPAS-299, ALCL; JURKAT and HD-MAR-2, T-cell leukaemia) to CHOP, a combination of drugs reflecting the regimen used in patients.13 Escalating doses of CHOP were used, and viable cell counting performed by flow cytometry.