Previous studies confirmed that ANXA8 is upregulated in numerous types of malignant tumors, such as acute promyelocytic leukemia [10], cholangiocarcinoma [11], breast cancer [12], and pancreatic cancer [13], but its relevant mechanisms have been rarely reported, and its roles in ovarian cancer have not yet been elucidated. Here, ANXA8 is linked to cholangiocarcinoma.