ANXA1 and ovarian carcinoma: Bonome et al. also found that ANXA1 (P = 3.82E−9, fold change = − 2.654), ANXA4 (P = 2.64E−8, fold change = − 3.067), and ANXA5 (P = 4.43E−7, fold change = − 2.849) were downregulated in ovarian cancer [22].