INS and Alzheimer disease: Though most of these correlations lost full significance after FDR adjustment, they are in line with our reported dominance (Firmicutes phylum, Christenellaceae family, Staphylococcus genus) or depletion of specific bacteria taxa (Bifidobacteriaceae family, Bifidobacterium genus) in adult mice with genetically induced Alzheimer’s type pathology13, and with the evidence that Lactobacillus- and Bifidobacterium-based probiotics ameliorate minimental state examination score (+27%) and insulin sensitivity (+28%) in patients with Alzheimer’s disease in 12 weeks60.