NF2 was affected in 44% of our tumor samples (n = 8/18) by frameshift mutations (n = 4/18), stop-gain mutations (n = 3/18) and splicing error (n = 1/18), which is in accordance with the literature as the primary inactivated tumor suppressor in meningiomas [6, 9, 28]. This evidence concerns the gene NF2 and neoplasm.