PM2.5–10 exposure was inversely associated with cg12124767 on CFTR gene (p = 9.86 × 10−8), which encodes the cystic fibrosis transmembrane conductance regulator, mainly involved in the pathogenesis of cystic fibrosis, but its function is reduced also due to environmental exposure, such as tobacco smoke [74]. The gene discussed is CFTR; the disease is cystic fibrosis.