The TRIB1 rs17321515 GA + AA genotypes were the significant risk factor for the development of CHD in NAFLD patients (OR = 1.760; 95% CI: 1.071–2.891; P = 0.026), after adjusted for age, gender, and body mass index, the risk of TRIB1 rs17321515 GA + AA genotypes were still marked (OR = 1.723; 95% CI: 1.033–2.873; P = 0.037) (Table 5). This evidence concerns the gene TRIB1 and metabolic dysfunction-associated steatotic liver disease.